We are independent & ad-supported. We may earn a commission for purchases made through our links.
Advertiser Disclosure
Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.
How We Make Money
We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently of our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.
Diet

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

What Is Hyaluronan?

By Jacquelyn Gilchrist
Updated: Mar 03, 2024

Hyaluronan is a medication prescribed for the treatment of osteoarthritis. This treatment, sometimes called viscosupplementation, is used for affected knee joints. It works like the natural synovial fluid in the joint to cushion it and provide lubrication to reduce pain and improve mobility. Patients will typically try other treatment methods first before using this drug.

This medicine is injected into the affected joint by a doctor or nurse. Patients will not typically inject it themselves at home. Sometimes, the doctor will need to aspirate, or withdraw, excess fluid from the joint before administering the injection. Patients may notice temporary swelling or pain at the injection site following each dosage. For the next 48 hours, they must avoid weight-bearing activities like jogging, any other strenuous activity, or prolonged standing.

Adults will usually receive a dosage of hyaluronan once per week for about three to four weeks. Patients may not notice the full benefit of the medicine until after the third injection. The dosages will vary, depending on each person's individual needs and their response to the treatment.

Some side effects may occur with the use of hyaluronan to treat osteoarthritis of the knee, which should be reported to the prescribing physician if they become severe. In addition to temporary swelling and pain of the knee, a rash or minor bruising may occur at the injection site. Patients have also reported a general achy feeling, and headaches and warmth or redness at the knee may also occur.

More serious side effects require a doctor's urgent care. Patients receiving hyaluronan should go to the emergency room immediately if they experience a fever, a rapid or pounding heartbeat, or a severe headache. Back pain and tingling skin have also been reported. Some people may suffer an allergic reaction to hyaluronan, which may present with tightness in the chest, severe dizziness, and trouble breathing. Allergic reactions may also cause facial swelling, a rash, and itching.

Before using hyaluronan injections for osteoarthritis, patients must disclose their other medical conditions, medications, and supplements to avoid a potential interaction. Women who are pregnant or breastfeeding should discuss the potential risks with their doctors. Those with an allergy to any bird or egg products, including bird feathers, should avoid this injection. It is contraindicated for use by those with a skin disease or infection at the injection site. Patients should also inform the doctor if they have a history of joint infections or circulation problems.

The Health Board is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.
Discussion Comments
Share
The Health Board, in your inbox

Our latest articles, guides, and more, delivered daily.

The Health Board, in your inbox

Our latest articles, guides, and more, delivered daily.