What Is Hyoscine Hydrobromide?

Maggie J. Hall
Maggie J. Hall
Hyoscine hydrobromide is often used to treat motion sickness.
Hyoscine hydrobromide is often used to treat motion sickness.

Hyoscine hydrobromide, also known as scopolamine or levo-duboisine, comes from the nightshade plant family and is often used for the treatment of motion sickness. Manufacturers may combine scopolamine with other medications or produce a derivative of the drug. These medications are frequently prescribed for respiratory symptoms or gastrointestinal disorders. Historically, individuals have used hyoscine hydrobromide for criminal and recreational purposes and well as for medical reasons.

Hyoscine hydrobromide is sometimes used to great the muscle spasms from colic.
Hyoscine hydrobromide is sometimes used to great the muscle spasms from colic.

The Datura or jimson weed plants produce the belladonna alkaloid used to formulate hyoscine hydrobromide. Also referred to as a tropane alkaloid drug, scopolamine acts by binding to the muscarinic acetylcholine receptors of the central nervous system and smooth muscle. This action inhibits the transmission of acetylcholine, producing an anticholinergic effect. It is thought that the muscarinic antagonist also affects these receptors in the vestibular area of the inner ear, thus inhibiting signals that produce nausea and vomiting.

Possible side effects of hyoscine hydrobromide include blurred vision and a rapid pulse.
Possible side effects of hyoscine hydrobromide include blurred vision and a rapid pulse.

The anticholinergic properties of hyoscine hydrobromide often produce side effects that include drowsiness and decreased motor function, which may cause a lack of physical coordination. By relaxing the smooth muscles, the medication decreases excretory gland function, inhibiting gastric secretions, perspiration, and salivation. Urinary retention is also a common side effect. Scopolamine usually causes pupil dilation, which may lead to blurred vision, and some individuals may experience an increase in heart rate as well.

Side effects of hyoscine hydrobromide may include drowsiness.
Side effects of hyoscine hydrobromide may include drowsiness.

Physicians might administer hyoscine hydrobromide prior to anesthesia and surgery in the form of a transdermal patch applied behind the ear. The medication generally eliminates post-operative nausea. Some physicians prescribe methscopolamine bromide in tablet form as part of an ulcer treatment regimen. In some countries, scopolamine is used to reduce the painful muscle spasms associated with colic or irritable bowel syndrome. Scopolamine combined with chlorpheniramine maleate and phenylephrine dries secretions and relieves the nasal congestion that accompany allergies and colds.

Large quantities of hyoscine hydrobromide may create euphoria or hallucinations, which has led some to abuse the drug.
Large quantities of hyoscine hydrobromide may create euphoria or hallucinations, which has led some to abuse the drug.

During the early part of the 20th century, physicians used hyoscine hydrobromide and morphine prior to childbirth and surgery, as the medication reportedly produced amnesia. This adverse reaction allegedly makes the drug popular with the criminal element in some countries. Persons under the influence of the drug are reported to behave submissively, while having no memory of events. Scopolamine is also said to be one of the drugs used to induce zombie like states in Haitian culture.

In sufficient quantities, hyoscine hydrobromide may produce euphoria or hallucinations. These symptoms entice some to abuse it in conjunction with opioids. History also reports that certain occult practitioners used the plant in topical “flying ointments” and potions for its hallucinogenic properties.

You might also Like

Discussion Comments

anon926922

As I have some mild vertigo and constant ear problems (e.g., crackling and semi-blocked always) I was amazed that when I took this drug (in the form of Kwells) for a whale watch cruise, that I felt fantastic! My head felt "unblocked" and there was no trace of dizziness or unsteadiness... My questions are this: I wonder what I would feel like without the movement of the ocean and two, whether I could take them on a regular basis, like once a day. What are everyone's thoughts? I cannot describe how "alive" and "balanced" I felt.

Post your comments
Login:
Forgot password?
Register:
    • Hyoscine hydrobromide is often used to treat motion sickness.
      By: jedi-master
      Hyoscine hydrobromide is often used to treat motion sickness.
    • Hyoscine hydrobromide is sometimes used to great the muscle spasms from colic.
      By: Galina Barskaya
      Hyoscine hydrobromide is sometimes used to great the muscle spasms from colic.
    • Possible side effects of hyoscine hydrobromide include blurred vision and a rapid pulse.
      By: bellemedia
      Possible side effects of hyoscine hydrobromide include blurred vision and a rapid pulse.
    • Side effects of hyoscine hydrobromide may include drowsiness.
      By: Andres Rodriguez
      Side effects of hyoscine hydrobromide may include drowsiness.
    • Large quantities of hyoscine hydrobromide may create euphoria or hallucinations, which has led some to abuse the drug.
      By: Jacek Chabraszewski
      Large quantities of hyoscine hydrobromide may create euphoria or hallucinations, which has led some to abuse the drug.