We are independent & ad-supported. We may earn a commission for purchases made through our links.

Advertiser Disclosure

Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.

How We Make Money

We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently from our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.

What Is the Role of Estradiol in Men?

By T. Broderick
Updated Mar 03, 2024
Our promise to you
The Health Board is dedicated to creating trustworthy, high-quality content that always prioritizes transparency, integrity, and inclusivity above all else. Our ensure that our content creation and review process includes rigorous fact-checking, evidence-based, and continual updates to ensure accuracy and reliability.

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

Editorial Standards

At The Health Board, we are committed to creating content that you can trust. Our editorial process is designed to ensure that every piece of content we publish is accurate, reliable, and informative.

Our team of experienced writers and editors follows a strict set of guidelines to ensure the highest quality content. We conduct thorough research, fact-check all information, and rely on credible sources to back up our claims. Our content is reviewed by subject matter experts to ensure accuracy and clarity.

We believe in transparency and maintain editorial independence from our advertisers. Our team does not receive direct compensation from advertisers, allowing us to create unbiased content that prioritizes your interests.

The role of estradiol in men is limited but it plays a significant role in maintaining a man's reproductive capability. Estradiol is a sex hormone that regulates a woman's menstrual cycle. In men, the hormone is produced in much smaller amounts. The estradiol in men prolongs the lives of sperm cells, increasing the chances that during intercourse, viable sperm cells reach the ovum. If levels of estradiol in men are too high or low, it can have a negative effect.

Estradiol is a sex hormone produced by the ovaries in women and testes in men. In both cases, estradiol is converted from testosterone. Its role is best understood in regulating women's menstrual cycle. During a woman's menstrual cycle, a rising level of estradiol prompts the release of one ovum, or egg, from the ovaries. Levels are lowest during menstruation, but remain at their peak if a pregnancy occurs.

A typical adult male generally has anywhere between a fifth and half as much estradiol in his bloodstream than a comparable woman. This deficiency is natural as estradiol is an estrogen; high levels of estradiol lower sperm counts in men. Yet in low levels, estradiol has a positive effect on a man's ability to reproduce.

All cells eventually go through apoptosis, or programmed cell death. This process is essential to avoid the development of cancers and other ailments. The presence of estradiol in men delays apoptosis in sperm cells. As estradiol is only produced in the testes in men, sperm cells receive the maximum benefit from estradiol and have a higher chance of surviving the journey between the testes and ovum.

Though the proper level of estradiol in men can give a reproductive advantage, low or high levels can do more than affect reproduction. Research published in 2009 suggests that men with low or high levels of estradiol will more likely suffer from heart failure. Consequently, readjusting estradiol levels in men with heart failure increases heart functionality. The research notes, though, that its results are only preliminary and that it may take years for consistently effective estradiol treatments to become available.

Another, more serious complication from high estradiol in men is an increased risk of prostate cancer. A rise in estradiol and decrease in testosterone are both markers that a man's hormones have become imbalanced, an event that can occur after the age of 40. Though other factors such as genetics influence a man's chances of developing prostate cancer, annual blood tests can reveal a hormone imbalance before cancer develops. Early detection is key in reducing a man's chances of dying from prostate cancer.

The Health Board is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.

Discussion Comments

The Health Board, in your inbox

Our latest articles, guides, and more, delivered daily.

The Health Board, in your inbox

Our latest articles, guides, and more, delivered daily.