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How Do I Choose the Best Prednisone Alternatives?

By Helena Reimer
Updated: Mar 03, 2024

Prednisone is one of the synthetic corticosteroids that is used to treat cancer, headaches, and a variety of inflammatory diseases. It is an immunosuppressant drug that often causes severe side effects that have prompted some to look for different treatments. Some alternatives include Chinese and other herbs, anti-inflammatory foods, and foods that help to naturally numb the pain. In order to choose the best prednisone alternatives, it is important to note what condition you are taking it for and then take the appropriate remedies that fight that particular condition.

In cases of cancer, the best alternatives for prednisone are foods that naturally contain cancer-fighting agents. These alternatives include antioxidant-rich foods, such as tomatoes, blueberries, and spinach. Lingzhi, ku shen, and gan cao are three Chinese herbs that can be formulated into an herbal preparations that is said to be an effective combination. Other herbs that can serve as an alternative include dong quai, aloe vera, and feverfew.

Migraines and other forms of headaches are often treated with prednisone to help ease the pain. Therefore, the best alternatives are remedies that help ease the pain in a similar manner. Chamomile and white willow bark tea, as well as essential oils obtained from lavender, peppermint, or rosemary, have been shown to be effective in easing pain. Other natural painkillers include hot and spicy foods, such as cayenne pepper and ginger. Supplements that contain amino acids, certain minerals, and B vitamins have also shown to be effective in reducing pain and inflammation.

Anti-inflammatory foods can serve as a great prednisone alternative in cases of inflammatory diseases, such as arthritis, asthma, and inflammatory bowel disease. These foods include fish, nuts, seeds, and other foods that are high in omega-3 fatty acids. Quercetin also has anti-inflammatory properties, which can be found in onions, garlic, and many fruits. In addition to consuming plenty of anti-inflammatory foods, it is just as important to avoid saturated fats, sugar, and other processed foods that contribute to inflammation.

The side effects of prednisone can be severe, especially after a prolonged use of the corticosteroid drug. Short-term side effects include high blood sugar levels, insomnia, and mania. It suppresses the immune system, which in the long term increases the risk for infections and other immune disorders. Many other treatments can deliver some of the same benefits, however, without the same short- or long-term side effects, when taken in moderation.

The Health Board is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.
Discussion Comments
By anon345722 — On Aug 21, 2013

Please try L-Tyrosine. It will make a headache and anxiety go away in an hour. Take the capsules, not caplets -- 500 mg are $6 at the local vitamin store. I started taking it in the 80s for massive headaches from cocaine withdrawal. It stops the depression you get from withdrawal. It just makes you feel like doing something but suffer.

By SarahSon — On Jun 03, 2011

If you are taking Prednisone because of inflammation, there are some dietary choices you can make that can be very beneficial. There are many natural alternatives to medicine and healthy food is one of them.

If you add some Omega 3 oils to your diet such as found in salmon, that can help with inflammation and your overall general well being. I don't like the taste fish, so take a natural supplement that has the Omega 3 oils in it.

There are times when nothing works as good as the Prednisone does, but by making some changes in your diet, you can often reduce the amount of medication that you have to take.

By julies — On Jun 02, 2011

Migraine headaches have been a part of my life for many years. It seems like I have tried everything I can think of the get rid of these headaches with natural methods. There times when the only thing that helps is steroids, but I have been looking for a natural alternative to prednisone.

I was introduced to essential oils and told that peppermint will often help with headaches. For me, I have found that using a combination of peppermint and wintergreen essential oils rubbed on my temples and the middle of my forehead work very well. The key is to apply as soon as I feel a headache coming on. If I wait too long, the essential oils don't usually work, but it is nice to have a natural remedy that will help.

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