We are independent & ad-supported. We may earn a commission for purchases made through our links.
Advertiser Disclosure
Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.
How We Make Money
We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently of our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.

Is It Safe to Combine Phentermine and Alcohol?

By S. Berger
Updated Mar 03, 2024
Our promise to you
The Health Board is dedicated to creating trustworthy, high-quality content that always prioritizes transparency, integrity, and inclusivity above all else. Our ensure that our content creation and review process includes rigorous fact-checking, evidence-based, and continual updates to ensure accuracy and reliability.

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

Editorial Standards

At The Health Board, we are committed to creating content that you can trust. Our editorial process is designed to ensure that every piece of content we publish is accurate, reliable, and informative.

Our team of experienced writers and editors follows a strict set of guidelines to ensure the highest quality content. We conduct thorough research, fact-check all information, and rely on credible sources to back up our claims. Our content is reviewed by subject-matter experts to ensure accuracy and clarity.

We believe in transparency and maintain editorial independence from our advertisers. Our team does not receive direct compensation from advertisers, allowing us to create unbiased content that prioritizes your interests.

Phentermine is a medication related to amphetamines used to suppress the appetite, helping individuals to lose weight. Generally, it is only taken for short periods of time to minimize its potentially habit-forming properties, and to reduce the risk of certain harmful side effects such as changes in heart rate, blood pressure, and sleep habits. The consensus among most medical professionals is that, due to potential interactions in the brain and body, it is not safe to mix phentermine and alcohol. Unlike certain medications, however, the combination of the two is not likely to prove life-threatening.

One of the main risks of combining phentermine and alcohol is the chance of increasing the side effects of the medication. Some of the side effects of phentermine can include nausea, stomach discomfort, and heartburn. Alcohol can potentially cause these effects as well, because it acts as an irritant to the stomach lining, and triggers the release of acid in the stomach, which can further exacerbate these symptoms. Taken together, these two substances could cause unpleasant sensations even when combined in small amounts.

Phentermine can cause confusion and disorganized thinking, particularly when an individual is first getting used to the medication. Drinking alcohol can also impair judgment, and can often increase the sense of confusion created by other substances. Mixing phentermine with alcohol can therefore cause dangerous mental effects, and can interfere with the ability to make sound decisions. Driving, operating machinery, and other potentially dangerous tasks should never be attempted if these two substances are taken at once.

Manufacturer's warnings provided with this medication also warn that combining phentermine and alcohol may create feelings of dizziness and lightheadedness. This combination is not likely to cause unconsciousness in small doses, but an individual taking both may fear that possibility. In turn, this could trigger feelings of nervousness, which are already possible when taking phentermine alone. Taking both substances may also worsen the insomnia that can result from phentermine usage.

Both phentermine and alcohol have the capacity to be habit-forming. Individuals with a history of alcohol abuse should avoid taking phentermine and alcohol together, as it could increase the risk of misusing the medication. This type of misuse could also lead to impaired judgment and problems with decision making. Like the other adverse effects that can come about as a result of mixing theses substances, this abuse may not be immediately life-threatening. There is the possibility of these effects leading to even more dangerous consequences over time, however, which is why this combination is not considered safe.

The Health Board is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.
Discussion Comments
By anon1002854 — On Mar 04, 2020

I just started taking phentermine 2 days ago and in 2 weeks I am supposed to go have a few drinks with some friends. Do you think I will be OK to do this?

By anon995971 — On Jun 18, 2016

I am on prescribed Phentermine and have not stopped going out two to three times a week and having three to four glasses of wine in an evening. It does not give me a hangover at all other than a slight headache now and then? Still losing weight in my second month and never felt better!

By anon359065 — On Dec 14, 2013

I have taken phentermine 37.5 mg daily on and off for two and a half years. I usually take the phen between 7 and 10 am and on the days I have consumed alcohol, I usually drank between 4 pm and 11 pm. I have never noticed any effects other than I seem to get drunk somewhat quicker. Hangovers are no worse, and I rarely get hangovers since I don't have to drink as much to feel drunk while taking phentermine.

By anon329402 — On Apr 09, 2013

I have swelling in my face. I will have two beers before bed just to bring me down a little, just so I can sleep. When I wake up I look like I drank all night.

By serenesurface — On Oct 08, 2012

@burcinc-- I second what @burcidi said. I'm not on phentermine but my boyfriend is and the one time he drank while on the drug, he was completely crazy. He told me that he was feeling a lot of anxiety and he seemed to have so much energy but he really didn't know what he was doing. It was like he lost control of himself. He also had a bad hangover and stayed in bed the whole next day.

I don't think it makes sense to combine these two anyway. Alcohol has a lot of calories, so it's really not the best thing to drink when you're trying to lose weight and taking medications for it.

By burcidi — On Oct 07, 2012

@burcinc-- Yea, I had some wine last weekend and I've been on phentermine since last month. It was actually really bad. I have a high tolerance for alcohol but because of the phentermine, the wine hit me badly. I had, literally, the worst hangover of my life.

I had lightheadedness shortly after and a couple of hours after that, I had nausea, migraine and started vomiting. It was such a bad idea to mix those two, I will never do it again.

By burcinc — On Oct 06, 2012

Just curious, has anyone actually had a drink or two while on phentermine?

Did you get bad side effects like the ones mentioned in the article?

The Health Board, in your inbox

Our latest articles, guides, and more, delivered daily.

The Health Board, in your inbox

Our latest articles, guides, and more, delivered daily.