We are independent & ad-supported. We may earn a commission for purchases made through our links.
Advertiser Disclosure
Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.
How We Make Money
We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently of our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.
Conditions

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

What are the Most Common Reactions to Amoxicillin?

By Jeremy Laukkonen
Updated: Mar 03, 2024

Most common reactions to amoxicillin tend to be caused by allergies. A smaller amount of people may experience a non-allergic rash that tends to appear several days after taking amoxicillin. Allergic reactions can range from mild to severe cases of itching, nausea, and vomiting, and it is typically recommended to contact a doctor as soon as they are noticed. Certain patients have also reported other reactions, including mental changes, anxiety and insomnia. In cases where an overdose of amoxicillin is ingested, common reactions can begin with lethargy and potentially end in a failure of the renal system.

Some people are allergic to beta-lactam antibiotics like amoxicillin, so it may be recommended to carefully monitor the presence of potential side effects when taking one of these drugs for the first time. When allergic reactions to amoxicillin occur, they typically begin with an itching sensation. The itching may be localized in the tips of the fingers and the groin, though it will typically spread quickly to other locations. Itching may also be accompanied by a rash.

Further reactions to amoxicillin will typically take the form of nausea, and may lead to vomiting or diarrhea. A fever can also develop, though this may not be noticed if the illness the amoxicillin was meant to treat already involved a fever. All of these common reactions to amoxicillin can become serious very quickly, and both vomiting and diarrhea can lead to dehydration. It may be wise to seek medical attention at the first onset of symptoms.

A non-allergic rash may also occur in a smaller number of cases. While these rashes will often closely resemble allergic reactions, a medical professional will typically be able to tell the difference. These rashes are usually itchy and usually occur about three days after amoxicillin is first taken. Those with mononucleosis caused by the Epstein-Barr virus may be far more likely to experience this type of non-allergic reaction to amoxicillin than others.

Regardless of the type or severity of a side-effect, contacting a doctor is typically the best way to deal with reactions to amoxicillin. If it is an allergic reaction, the symptoms may develop very quickly and become severe and potentially even life threatening. In cases where reactions like these are experienced, beta-lactam antibiotics like amoxicillin will usually be avoided in treating future illnesses. A non-allergic amoxicillin rash, however, will not prevent further prescriptions of this class of medication.

The Health Board is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.
Discussion Comments
By donasmrs — On Mar 13, 2013

@ZipLine-- I have nausea and diarrhea with amoxicillin too. But I've noticed that if I take the medication on a full stomach, along with a glass of milk, it's much better.

It's also good to take probiotics while on amoxicillin, to replace the good bacteria the medication kills in our gut and intestines. You will have less diarrhea if you do that.

By burcidi — On Mar 12, 2013

Does anyone experience symptoms similar to a seasonal allergy when they're on amoxicillin?

I've been taking amoxicillin for a tooth infection and have been experiencing some allergic symptoms. I don't have a rash, I just feel drowsy, kind of confused and I also have watery eyes. I only get these symptoms when I'm having seasonal allergies and I know I'm not right now. It's so weird.

Could these be rare side effects of amoxicillin?

By ZipLine — On Mar 11, 2013

Amoxicillin gives me very bad diarrhea. Most antibiotics do actually, that's why I hate taking antibiotics.

Share
https://www.thehealthboard.com/what-are-the-most-common-reactions-to-amoxicillin.htm
The Health Board, in your inbox

Our latest articles, guides, and more, delivered daily.

The Health Board, in your inbox

Our latest articles, guides, and more, delivered daily.