We are independent & ad-supported. We may earn a commission for purchases made through our links.
Advertiser Disclosure
Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.
How We Make Money
We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently of our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.

What Causes Abnormal Lymphocytes?

By Jennifer Long
Updated Mar 03, 2024
Our promise to you
The Health Board is dedicated to creating trustworthy, high-quality content that always prioritizes transparency, integrity, and inclusivity above all else. Our ensure that our content creation and review process includes rigorous fact-checking, evidence-based, and continual updates to ensure accuracy and reliability.

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

Editorial Standards

At The Health Board, we are committed to creating content that you can trust. Our editorial process is designed to ensure that every piece of content we publish is accurate, reliable, and informative.

Our team of experienced writers and editors follows a strict set of guidelines to ensure the highest quality content. We conduct thorough research, fact-check all information, and rely on credible sources to back up our claims. Our content is reviewed by subject-matter experts to ensure accuracy and clarity.

We believe in transparency and maintain editorial independence from our advertisers. Our team does not receive direct compensation from advertisers, allowing us to create unbiased content that prioritizes your interests.

There are several causes of abnormal lymphocytes. A few differences distinguish these lymphocytes from their typical counterparts. Lymphocytes can be abnormal if their size, shape, or numbers stray away from normal classifications. Common causes of these abnormalities include any illness, condition, or disease that affects white blood cells. Examples include auto-immune conditions, reactive lymphocytes, and lymphoma.

Lymphocytes are a type of white blood cell that falls into one of two groups. Granular lymphocytes are called natural killer cells, while small lymphocytes are made by the lymph nodes and are vital parts of the immune system. Any interference with these white blood cells can lead to abnormal lymphocytes.

Abnormal lymphocytes are found by testing either blood samples or lymph fluid from the lymphatic system. The amount, size, and shape of lymphocytes found in the sample are examined, helping doctors find the reason for the abnormality. Many factors can influence normal lymphocytes.

One of the common causes of abnormal lymphocytes is an auto-immune condition, wherein the immune system attacks itself. The cells of the immune system confuse the body’s cells with invading cells and the immune system kills these cells. Lymphocytes are abnormal in this instance because their count is low.

Lymphocytes that become reactive are also abnormal. In this instance, these white blood cells are exposed to foreign antigens. Upon exposure, the lymphocytes become abnormally large. Hepatitis C and the Epstein-Barr virus can lead to this change in size.

Lymphoma generally causes T cells and B cells to become abnormal lymphocytes. Lymphocytes become cancerous in the lymph nodes. Typically, lymphoma results from cancerous B cells but can also occur from abnormal T cells.

Lymphocytopenia is a type of disorder that directly causes abnormal lymphocytes. More specifically, lymphocytopenia causes a low lymphocyte count. Lymphocytes can be trapped in the organs of the lymphatic system, produced and destroyed, or not produced at all. This disorder is frequently caused by serious conditions, such as an auto-immune condition.

Viral infections and sometimes leukemia can lead to lymphocyte counts being higher than usual. The presence of virus cells triggers the immune system’s responses. As a response to the invasion, more lymphocytes are made to combat and remove the virus cells, preventing these cells from causing damage.

The Health Board is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.
Discussion Comments
By anon978972 — On Nov 23, 2014

What causes abnormally shaped white blood cells, specifically holes in white blood cell (probably monocyte) walls?

The Health Board, in your inbox

Our latest articles, guides, and more, delivered daily.

The Health Board, in your inbox

Our latest articles, guides, and more, delivered daily.