We are independent & ad-supported. We may earn a commission for purchases made through our links.
Advertiser Disclosure
Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.
How We Make Money
We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently of our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.

What Is Triclabendazole?

By Jillian O Keeffe
Updated Mar 03, 2024
Our promise to you
The Health Board is dedicated to creating trustworthy, high-quality content that always prioritizes transparency, integrity, and inclusivity above all else. Our ensure that our content creation and review process includes rigorous fact-checking, evidence-based, and continual updates to ensure accuracy and reliability.

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

Editorial Standards

At The Health Board, we are committed to creating content that you can trust. Our editorial process is designed to ensure that every piece of content we publish is accurate, reliable, and informative.

Our team of experienced writers and editors follows a strict set of guidelines to ensure the highest quality content. We conduct thorough research, fact-check all information, and rely on credible sources to back up our claims. Our content is reviewed by subject-matter experts to ensure accuracy and clarity.

We believe in transparency and maintain editorial independence from our advertisers. Our team does not receive direct compensation from advertisers, allowing us to create unbiased content that prioritizes your interests.

Triclabendazole is a drug that may be used in humans, but is more commonly used in herd animals. Typically, its role is as a treatment for a disease called fascioliasis, which is caused by liver flukes. While cows, sheep and goats are the usual populations in which the fluke is found, people can also pick it up, especially in regions that lack sufficient clean water supplies. Although human use is approved in some countries, others, like the U.S. and Canada, do not allow it. Possible side effects of triclabendazole use, as of 2011, appear to be restricted to temporary digestive tract issues.

Fascoliasis is a disease that is caused by worms, generally of the Fasciola and Fascioloides species. Paragonimiasis is another fluke disease that can be treated with triclobendazole, which is caused by Paragonimus species. These worms infect herd animals and can contaminate the environment, passing to humans through unwashed and uncooked vegetables. Animals infected with fascoliasis and paragonimiasis can receive treatment with triclabendazole, and those animals in the same herd may also receive it in case they have contracted the disease. Humans normally only receive triclabendazole when they are diagnosed with infections like fascoliasis, and this is most common in regions such as the Andes, Egypt and Iran.

The flukes that cause fascoliasis and paragoniasmus go through various stages in their lifecycle, from tiny egg to adult worm. Triclabendazole can kill all stages of the fluke from the point when the immature worm comes out of the egg up to the adult stage, but it cannot kill the egg itself. This is due to its particular mode of action, which involves breaking down the structure of the worm and interfering with its ability to make proteins. These effects also prevent the fluke from moving around the body, as the structural components that help it move are affected.

As of 2011, triclabendazole does not appear to produce any serious side effects in people, apart from effects that are a result of the dead flukes clogging up the body; this especially occurs in areas such as the bile duct, which is connected to the liver. Recognized intrinsic side effects commonly involve the gastrointestinal tract, such as diarrhea, but these pass with time. People who undergo treatment with triclabendazole may need to supply samples like stool samples to their doctor after a course of the drug to check that the medication is clearing the infection.

The Health Board is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.
Discussion Comments
The Health Board, in your inbox

Our latest articles, guides, and more, delivered daily.

The Health Board, in your inbox

Our latest articles, guides, and more, delivered daily.