We are independent & ad-supported. We may earn a commission for purchases made through our links.
Advertiser Disclosure
Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.
How We Make Money
We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently of our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

What Are the Effects of Putting Eye Drops in a Drink?

By Christina Edwards
Updated: Mar 06, 2024

Eye drops are meant to be used directly on the eyes, but they may sometimes be misused and administered with other methods, intentionally or unintentionally. Putting eye drops in a beverage can cause the person who drinks it some severe side effects. The active ingredient in some medical eye drops can cause symptoms such as nausea and vomiting. A severe drop in blood pressure and body temperature could also occur, and a person could even slip into a coma and die.

One of the most popular urban legends involves eye drops in a drink. The legend states that if a victim ingests just a couple drops of this eye medicine, he will suffer from diarrhea for a few hours. This urban legend has often been popularized by the media, showing up in various movies.

Regular saline eye drops will not typically have any effect on a person, if ingested. Only medical eye drops designed to minimize red eyes will cause problems when they are ingested. These typically contain an active ingredient known as tetrahydrozoline, which helps constrict blood vessels.

Ingestion of tetrahydrozoline via eye drops in a drink can cause severe nausea, but not usually diarrhea. Vomiting, on the other hand, is common in people who ingest this substance. Blurred vision and tremors can also occur. It usually only takes a couple of drops to cause these symptoms, though larger amounts can cause much more serious problems.

Tetrahydrozoline can also cause other, more serious, problems. The blood pressure of a person who ingests eye drops in a drink can possible rise and drop suddenly. His body temperature may also drop to dangerously low levels. Seizures can also occur, and a person may even slip into a coma. If left untreated, ingesting eye drops may even prove fatal.

Putting eye drops in a drink is not just harmless fun. After seeing it on movies or hearing about it through the grape vine, some people have even tried it. Some have given eye drops to friends as a joke, while others have tried to make their enemies uncomfortable.

In the United States, putting eye drops in a person's drink is considered attempted poisoning. This is a serious crime with some serious repercussions. Some defendants may even get jail time for an offense that began as a supposedly harmless prank.

What is the History of the Visine Prank?

Like many of these trends, this began as a prank in movies and television. It is known as the “Visine Prank”, and searching for it online will yield results as far as 2003. After appearing in popular movies like “Wedding Crashers” and TV shows such as “CSI”, it has again gained prominence through social media sites like Facebook, Twitter, and TikTok.

Because of the way it was portrayed in fiction, many people got the idea that using over-the-counter eye drops was a cheap way to cure their digestive issues. Some even treated family members if they had eye drops, but no laxatives were on hand. 

Dire consequences could come from treating stomach conditions with eye drops containing tetrahydrozoline. Interestingly, diarrhea is believed to be caused by eye drops, but that is not one of the side effects.

What Happens to Your Body When You Ingest Tetrahydrozoline?

Eye Drops that contain tetrahydrozoline reduce redness in the eyes by constricting the blood vessels. The effects are temporary, and it is not recommended to use them for long periods since you can develop a dependency on them.

Over time they become less effective, and stopping them can cause a reverse condition where your eyes are even redder than they were before. Overusing the drops can cause illness, including vomiting and blood pressure changes.

There are also nasal sprays that contain tetrahydrozoline. They use the same science to help stop a runny nose for a short time. Again, there are many adverse side effects to using these products for too long. And they can also cause dependency, resulting in a difficulty dealing with nasal issues without using the medication.

When someone puts a few drops of tetrahydrozoline into someone’s drink, it can cause blood vessels to constrict in other parts of the body.

Dizziness, unconsciousness, vomiting, low or high blood pressure, and hypothermia are common side effects. And since someone pulls the prank on someone, that someone is probably not going to measure how much they dose them with, it is easy for someone to overdose.

How is a Tetrahydrozoline Overdose Treated?

There is no antidote for tetrahydrozoline. If you know that someone has been poisoned with it or start showing signs of ingestion, you should call poison control immediately. They will probably need to be taken to the emergency room so they can be treated for their symptoms and observed by medical personnel.

They can be given a medicine called activated charcoal that will keep their body from absorbing more of the chemical than they already have. It acts as a filter and helps the chemical move through the body.

After that, all doctors can do is give the victim fluids and treat their symptoms. If their blood pressure is abnormal, they can be treated for that as needed. Anti-nausea medicines will help control vomiting. The fluids help with that as well.

What is the Punishment for Tetrahydrozoline Poisoning?

Someone that knowingly puts eyedrops or some other form of tetrahydrozoline into someone’s drink can be charged with anything from assault to attempted murder. 

In 2020 Lana Sue Clayton of South Carolina was charged with poisoning her husband with the chemical by putting eye drops in his drinks. She continually dosed him for three days to make him uncomfortable after an argument. The amount of medicine he ingested was enough to kill him. Clayton was sentenced to 25 years in prison.

In 2013, a home daycare operator in Ontario was accused of poisoning two of the children in their care. They got very ill and had to be taken to a hospital. She was sentenced to 6 years in jail.

Since there is no way to know how serious the reaction is going to be of someone who ingests tetrahydrozoline, a person that pulls these pranks is putting themselves in a difficult situation.

The outcome of the prank could lead to them facing minor charges that may result in fines and some possible jail time. But if the victim dies or has a life-altering reaction, the perpetrator could be facing decades behind bars.

It is a great risk to take just to pull a prank or to get some revenge on someone after a heated argument.

The Health Board is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.
Discussion Comments
By Melonlity — On Feb 01, 2014

What kind of crumb would dump eye drops in someone's drink as a prank? I think the most we ever did to each other in college was dump sugar in a beer when it was unguarded. That was a hoot, but harmless.

Going any further than that seems downright cruel. What the heck is wrong with some people?

On this page
The Health Board, in your inbox

Our latest articles, guides, and more, delivered daily.

The Health Board, in your inbox

Our latest articles, guides, and more, delivered daily.