We are independent & ad-supported. We may earn a commission for purchases made through our links.
Advertiser Disclosure
Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.
How We Make Money
We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently of our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.

What Are the Most Common Hydroxyzine Side Effects?

By Melissa Barrett
Updated Mar 03, 2024
Our promise to you
The Health Board is dedicated to creating trustworthy, high-quality content that always prioritizes transparency, integrity, and inclusivity above all else. Our ensure that our content creation and review process includes rigorous fact-checking, evidence-based, and continual updates to ensure accuracy and reliability.

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

Editorial Standards

At The Health Board, we are committed to creating content that you can trust. Our editorial process is designed to ensure that every piece of content we publish is accurate, reliable, and informative.

Our team of experienced writers and editors follows a strict set of guidelines to ensure the highest quality content. We conduct thorough research, fact-check all information, and rely on credible sources to back up our claims. Our content is reviewed by subject-matter experts to ensure accuracy and clarity.

We believe in transparency and maintain editorial independence from our advertisers. Our team does not receive direct compensation from advertisers, allowing us to create unbiased content that prioritizes your interests.

Hydroxyzine is an antihistamine, and most side effects common to the class are also possible with the medication. The most reported of hydroxyzine side effects is a dry mouth. Sleepiness, vertigo, and mild confusion are also frequent complaints.

One of the reasons that antihistamines such as hydroxyzine are prescribed is to dry mucus. Unfortunately, this often leads to reduced saliva as well. This is more noticeable when just beginning the medication. Often, frequent sips of water or chewing ice chips can ease the problem. Chewing sugarless gum can help as well.

Vertigo and mild confusion are common when taking antihistamines, and extra precautions should be taken when driving. In some cases, certain hydroxyzine side effects are the intended effect of the medication. When given to treat anxiety or insomnia, hydroxyzine is counted on to cause drowsiness. In most cases, these side effects diminish as the body develops a tolerance to the medication.

Other side effects of hydroxyzine are more generalized and may be persistent. Upset stomach and vomiting are possible. Headaches and blurry vision have also been reported. Some individuals using hydroxyzine for longer periods have experienced sustained weight gain.

Allergies to medicines used to treat allergies are relatively uncommon. Still, one of the rarer hydroxyzine side effects is a potentially serious allergic reaction. Sudden irritation of the skin with or without a rash may indicate a problem. Tremors, oral and facial swelling and difficulty breathing are more serious indications of an allergic reaction. Any individual developing these symptoms should immediately contact a medical professional.

Hydroxyzine has been shown to be addictive. In many instances, the chances of addiction are increased when the drug is used in conjunction with some other medications. In particular, individuals taking sedatives or tranquilizers are generally advised to avoid hydroxyzine.

Combination with other medications can increase the severity of many side effects of hydroxyzine. In other cases, it can produce other potentially serious drug interactions. Patients should notify their caregiver of all herbal remedies, over-the-counter medicines and prescription drugs that they are taking before beginning hydroxyzine doses.

Patients with high blood pressure or heart disease often can require closer supervision when taking hydroxyzine. In addition, its use in children and the elderly should also be closely monitored, as these groups are more susceptible to hydroxyzine side effects. As with many medications, the benefits of hydroxyzine use by pregnant women should clearly outweigh any potential risks.

The Health Board is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.
Discussion Comments
By Heavanet — On Mar 13, 2014

I agree with you Runducuri. The doctor should be able to give the patient information about these side effects and discuss other possible alternatives to hydroxyzine.

By Rundocuri — On Mar 12, 2014

There are many other types of antihistamine drugs that are more commonly prescribed than hydroxyzine because of its many potential side effects. I would recommend that anyone who is prescribed this medication should have a discussion with his or her doctor about the side effects of this medicine.

The Health Board, in your inbox

Our latest articles, guides, and more, delivered daily.

The Health Board, in your inbox

Our latest articles, guides, and more, delivered daily.