We are independent & ad-supported. We may earn a commission for purchases made through our links.
Advertiser Disclosure
Our website is an independent, advertising-supported platform. We provide our content free of charge to our readers, and to keep it that way, we rely on revenue generated through advertisements and affiliate partnerships. This means that when you click on certain links on our site and make a purchase, we may earn a commission. Learn more.
How We Make Money
We sustain our operations through affiliate commissions and advertising. If you click on an affiliate link and make a purchase, we may receive a commission from the merchant at no additional cost to you. We also display advertisements on our website, which help generate revenue to support our work and keep our content free for readers. Our editorial team operates independently of our advertising and affiliate partnerships to ensure that our content remains unbiased and focused on providing you with the best information and recommendations based on thorough research and honest evaluations. To remain transparent, we’ve provided a list of our current affiliate partners here.

What is a Calcium Channel?

Mary McMahon
Updated Mar 03, 2024
Our promise to you
The Health Board is dedicated to creating trustworthy, high-quality content that always prioritizes transparency, integrity, and inclusivity above all else. Our ensure that our content creation and review process includes rigorous fact-checking, evidence-based, and continual updates to ensure accuracy and reliability.

Our Promise to you

Founded in 2002, our company has been a trusted resource for readers seeking informative and engaging content. Our dedication to quality remains unwavering—and will never change. We follow a strict editorial policy, ensuring that our content is authored by highly qualified professionals and edited by subject matter experts. This guarantees that everything we publish is objective, accurate, and trustworthy.

Over the years, we've refined our approach to cover a wide range of topics, providing readers with reliable and practical advice to enhance their knowledge and skills. That's why millions of readers turn to us each year. Join us in celebrating the joy of learning, guided by standards you can trust.

Editorial Standards

At The Health Board, we are committed to creating content that you can trust. Our editorial process is designed to ensure that every piece of content we publish is accurate, reliable, and informative.

Our team of experienced writers and editors follows a strict set of guidelines to ensure the highest quality content. We conduct thorough research, fact-check all information, and rely on credible sources to back up our claims. Our content is reviewed by subject-matter experts to ensure accuracy and clarity.

We believe in transparency and maintain editorial independence from our advertisers. Our team does not receive direct compensation from advertisers, allowing us to create unbiased content that prioritizes your interests.

A calcium channel is a structure in the body which allows cells to transmit electrical charges to each other. These charges are carried on a calcium ion which can travel freely back and forth through the calcium channel. There are a number of different types of calcium channels, broken up by sensitivity and how they behave. This anatomical structure is part of a family of similar structures known collectively as ion channels.

Calcium channels are found in places like muscles, glial cells, and neurons. These types of cells are known as “excitable” cells. Different calcium channels work in different ways, but the general idea is that the structure is made from proteins which are sensitive to electrical impulses. When the proteins receive the right signal, they open the calcium channel, allowing an ion to flow across the channel to another cell.

Ions carry a small electrical charge which can stimulate something like a muscle contraction, the release of a hormone, or the firing of a neurotransmitter. At any given time, thousands of ions are moving around the calcium channels of the body, signaling various activities, ranging from heartbeats to speech. Different types of calcium channels behave in slightly different ways, or are sensitive to specific types of calcium ions, allowing the body great control over how and when these structures are active.

One could think of a calcium channel as a telephone line between cells. The line is always ready for use, and it swings into action when someone picks up the phone and dials a number, or when a calcium ion appears on one end of the line with the goal of ending up on the other side. Once the ion reaches its goal, the change in electrical potential in the destination cell causes something to happen, just as a phone call asking someone to pick up some milk at the store eventually results in a jug of milk appearing in the fridge.

A class of drugs known as calcium channel blockers or calcium channel antagonists is used to manage a variety of medical conditions. Classically, these drugs are used in the treatment of high blood pressure. The drugs block the action of the calcium channels in the heart, which means that the heart contracts less, since it receives fewer messages to do so, and this in turn reduces blood pressure. These drugs are also used to manage some neurological conditions, along with issues like migraines.

The Health Board is dedicated to providing accurate and trustworthy information. We carefully select reputable sources and employ a rigorous fact-checking process to maintain the highest standards. To learn more about our commitment to accuracy, read our editorial process.
Mary McMahon
By Mary McMahon

Ever since she began contributing to the site several years ago, Mary has embraced the exciting challenge of being a The Health Board researcher and writer. Mary has a liberal arts degree from Goddard College and spends her free time reading, cooking, and exploring the great outdoors.

Discussion Comments
By ellafarris — On Jun 16, 2011

@whitesand - Most calcium channel blockers have side effects that cause swollen feet, ankles and joints. Unfortunately nicardipine is one of them.

She should tell her physician right away and maybe he/she can prescribe a new drug or possibly the same one in a lower dose.

I'm not an expert on high blood pressure medications, but I do know that this one is an l-type calcium channel which means it is long lasting and will remain in her system for a while.

By whitesand — On Jun 14, 2011

What are some of the side effects of calcium channel blockers? My mother has been taking blood pressure medication for several years with no problems.

Recently her doctor switched her prescription to nicardipine and now her feet and lower legs are swollen beyond belief. Is this a common side effect for this particular drug?

Mary McMahon
Mary McMahon

Ever since she began contributing to the site several years ago, Mary has embraced the exciting challenge of being a...

Learn more
The Health Board, in your inbox

Our latest articles, guides, and more, delivered daily.

The Health Board, in your inbox

Our latest articles, guides, and more, delivered daily.