What Is a Tortuous Aorta?

A tortuous aorta is an aorta with anatomical abnormalities which cause it to be distorted in shape or path. Some people have a tortuous aorta and experience no ill health effects as a result of their slightly unusual anatomy, while others can experience complications. This condition can be diagnosed with the use of medical imaging studies which reveal the structure of the aorta and other blood vessels in the body. Such studies may be performed for unrelated reasons, or because a doctor suspects that a patient has an aorta abnormality.

The aorta is the largest blood vessel in the body. It carries freshly oxygenated blood out of the heart so that it can be distributed to the circulatory system. In most people, the aorta follows a relatively straight path, but in people with tortuous aorta, the vessel may be twisted or distorted. This can cause blockages in blood flow, leading to medical complications as a result of poor circulation.

Individuals with this condition can be at risk for high blood pressure caused by the interruption to their blood flow, and they can also experience atherosclerosis, in which the vessels are lined with a layer of plaque which impedes the movement of blood through the vessels. Tortuous aorta has also been implicated in some cases of pain caused by a displaced esophagus, as the twistings of the vessel can actually push the esophagus out of position.

When imaging studies are used to identify a tortuous aorta, they can provide information about the severity of the abnormality and the condition of the vessel. If deposits are present or the vessel appears to be hardening, steps may need to be taken before the patient experiences the development of serious complications. In other instances, the abnormality may simply be something which the doctor would recommended keeping an eye on, with no action being taken unless a need for it became apparent.

Having a tortuous aorta is not necessarily a cause for concern, but patients should make sure that it is noted in their medical charts because it may become relevant during treatment. In addition, surgeons usually like to know ahead of time about unusual anatomical features in their patients, and forewarning about an abnormal aorta is a good idea. The surgeon or surgical team may want to take special steps to protect the health of the patient.

Some people live their entire lives with the condition and never experience ill effects. It is something that should be monitored, however, because of the risks it poses. As long as it is not affecting a patient's life, a physician will usually recommend that it be left alone. On the other hand, if a patient is experiencing symptoms or the condition may cause complications in an unrelated procedure, there are a few options available.

The most common treatment for tortuous aorta is known as a bypass graft repair. This is similar to other types of bypass surgeries: a plastic tube (the graft) is inserted into the normal parts of the artery, literally bypassing the affected section of the aorta.

A second surgical treatment is a resection with end-to-end anastomosis. In this procedure, the twisted or narrowed section of the aorta is simply removed. Afterward, the two ends are reconnected (this is the actual anastomosis).

A less invasive treatment is balloon angioplasty. In this procedure, the physician uses a catheter to insert a small balloon into the affected part of the artery. When inflated, the balloon forces open the constriction. Once this is done, a stent, or small mesh tube, to maintain the opening.

One of the great advantages of balloon angioplasty is that it is performed as an outpatient procedure, requiring only local anesthesia. However, some medical experts question its long-term effectiveness.

There are also a few risks involved with balloon angioplasty. One of these is restenosis, a condition in which the artery narrows again, requiring the treatment to be repeated. Other risks include:

Scientists have determined that many cases of tortuous aorta are genetic. The condition has been traced to a mutation in the SLC2A10 gene ( a glucose carrier). The gene is autosomally recessive, meaning that the patient must have two copies of the gene in order for tortuous aorta syndrome to develop. It is too soon to tell if this knowledge will eventually lead to a cure, however. Another contributing factor is the degeneration and calcification of elastin, a protein that keeps organs resilient and flexible. Some research suggests that applying aluminum ions may help to reduce elastin calcification.

As explained earlier, a tortuous aorta is not immediately life-threatening, and many people are hardly aware they have the condition. However, it is a risk factor for developing an aortic aneurysm, in which the artery wall becomes weakened and in danger of bursting.

Unlike a tortuous aorta itself, an aneurysm can be very dangerous. An aneurysm is often described as a ticking time bomb; slow growing, it can be asymptomatic for years before it bursts.

Most other health dangers associated with a tortuous aorta stem not from the condition itself, but rather from reduced blood flow and its impact on adjacent organs, such as compression. This can be a serious problem when the twisted aorta exerts pressure on the esophagus, leading to breathing difficulties and chronic chest pain. 

Because an arterial kink restricts blood flow, hypertension (high blood pressure) can result. The reduced blood flow can also lead to muscular fatigue. Generally, if a patient is otherwise in good health, a tortuous aorta is not a serious problem. It can exacerbate other cardio-vascular issues, however.

Tortuous thoracic aorta is also frequently seen in elderly patients, in whom the cause is mild cases of atherosclerosis.

Most physical symptoms of tortuous aorta are so minor, most people with the condition hardly notice it. Symptoms that patients commonly report include:

Other symptoms occur in patients with a tortuous aorta-related aneurysm. As the condition worsens, patients may find themselves experiencing chest and/or back pain, coughing and hoarseness, hypotension (low blood pressure), breathing difficulties, and even loss of consciousness. A person suffering from tortuous aorta who experiences these symptoms should get to an emergency room at the earliest opportunity, especially if there is a family history of aneurysm. 

It is possible to live a normal life in spite of having tortuous aorta, or even an aneurysm. The key is avoiding things that may cause the problem to become worse. Avoid tobacco, limit alcohol consumption, watch LDL levels (the "bad" cholesterol) and avoid situations that increase stress and blood pressure levels.

A tortuous aorta is a condition where the aorta, the main artery that carries blood from the heart to the rest of the body, is twisted or bent. Many health issues, including reduced blood flow to the organs, an increased risk of stroke and aneurysm, and an increased chance of aortic dissection, can be brought on by this twisting or bending of the aorta.

The severity and location of an aortic twist might affect the symptoms of a twisted aorta. Chest pain, faintness, lightheadedness, shortness of breath, an accelerated heart rate, and pain or discomfort in the belly are typical symptoms. Even cardiac arrest or stroke might result from too much twisting. If you have any of these symptoms, it's crucial to get medical help.

Although the precise etiology of a twisted aorta is unknown, it is thought to be brought on by a confluence of hereditary and environmental factors. A twisted aorta can form as a result of some genetic disorders, including Marfan syndrome. A twisted aorta can also develop as a result of other environmental factors like smoking, obesity, and high blood pressure.

Imaging studies such as echocardiography, computed tomography (CT) scan, or magnetic resonance imaging are typically used to identify a convoluted aorta (MRI). These examinations can offer clear pictures of the aorta and can be used to spot any bending or twisting of the artery. Blood tests may also be prescribed by your doctor to look for any indications of organ damage brought on by the twisted aorta.

The severity of the illness and the symptoms present will determine the best course of treatment for a twisted aorta. In certain circumstances, making lifestyle adjustments like giving up smoking, eating healthier, and exercising frequently might assist with symptoms. To lower the chance of problems, doctors may also prescribe drugs such as beta-blockers and ACE inhibitors. Surgery may be required in more severe situations to repair the aorta and return normal blood flow.