Medicine
Fact-checked

At TheHealthBoard, we're committed to delivering accurate, trustworthy information. Our expert-authored content is rigorously fact-checked and sourced from credible authorities. Discover how we uphold the highest standards in providing you with reliable knowledge.

Learn more...

What Is Ibuprofen Toxicity?

Ibuprofen toxicity occurs when one ingests too much of this common pain reliever, leading to adverse effects on the body, particularly the liver and kidneys. Symptoms can range from nausea to severe organ damage. Understanding the risks and proper dosages is crucial for safe use. How can you protect yourself and your loved ones from the dangers of overconsumption?
Madeleine A.
Madeleine A.

Ibuprofen toxicity occurs when the body is unable to metabolize ibuprofen that has been consumed. Typically, ibuprofen toxicity is classified as minor toxicity, moderate toxicity, or major toxicity. When a patient has minor toxicity, symptoms include drowsiness, gastrointestinal symptoms, fast heart rate, low blood pressure, and skin irritation. Moderate ibuprofen toxicity may produce fever and seizures, while major toxicity may cause prolonged seizure activity, respiratory arrest, respiratory or cardiac arrest, and shock.

Taking doses of ibuprofen recommended by the manufacturer or health care provider are typically safe for most people. Problems tend to develop when ibuprofen is taken in higher-than-recommended doses or used for a long time. Non-steroidal anti-inflammatory drugs (NSAIDs) can be toxic to the kidneys, and in those who have renal insufficiency or other kidney conditions, taking ibuprofen should only be considered after it has been declared safe by the patient's health care provider.

Ibuprofen.
Ibuprofen.

Arthritis and other inflammatory conditions usually respond well when treated with ibuprofen. Not only does ibuprofen provide exceptional pain relief, it also decreases the swelling that is associated with arthritis as well. For those people who are at risk for ibuprofen toxicity, other methods of pain relief are available, including over-the-counter acetaminophen products. Ibuprofen is also effective in relieving the pain of sprains, muscle aches, headaches and toothaches. In addition, ibuprofen is also an effective fever reducer.

Ibuprofen is often the best choice for mild to moderate toothaches and headaches.
Ibuprofen is often the best choice for mild to moderate toothaches and headaches.

Even when toxic doses of ibuprofen are not consumed, serious side effects can occur, such as gastrointestinal bleeding. Ibuprofen toxicity may be more common in those who are taking other over-the-counter or prescription medications. Ibuprofen should not be taken with aspirin or other anticoagulants unless suggested by the health care provider. Although common in adults, ibuprofen toxicity can occur in children, and symptoms are similar to those of the adult. Parents should buy medicine in child-safety packages and keep medications out of the reach of children.

Anyone with symptoms of Ibuprofen toxicity should seek emergency medical care immediately.
Anyone with symptoms of Ibuprofen toxicity should seek emergency medical care immediately.

Sometimes, ibuprofen can cause fluid retention, characterized by swollen feet and ankles, facial puffiness, and swollen fingers. When this occurs, the health care provider should be called, because abnormal swelling may be a sign of kidney failure and ibuprofen toxicity. If symptoms of ibuprofen toxicity occur, emergency medical attention should be sought and the patient transported to the nearest hospital. Treatment may include gastric lavage, or pumping out the stomach of its contents, and the administration of intravenous fluids and medications.

You might also Like

Discuss this Article

Post your comments
Login:
Forgot password?
Register:
    • Ibuprofen.
      By: Richard Seeney
      Ibuprofen.
    • Ibuprofen is often the best choice for mild to moderate toothaches and headaches.
      By: Eléonore H
      Ibuprofen is often the best choice for mild to moderate toothaches and headaches.
    • Anyone with symptoms of Ibuprofen toxicity should seek emergency medical care immediately.
      By: william87
      Anyone with symptoms of Ibuprofen toxicity should seek emergency medical care immediately.
    • Children and the elderly are especially susceptible to bleeding risk associated with ibuprofen.
      By: Pavel Losevsky
      Children and the elderly are especially susceptible to bleeding risk associated with ibuprofen.
    • In some cases, ibuprofen helps mitigate pain that is caused by osteoarthritis or another inflammatory disease.
      By: Lisa F. Young
      In some cases, ibuprofen helps mitigate pain that is caused by osteoarthritis or another inflammatory disease.
    • While consuming the recommended dosage of ibuprofen is typically safe, taking more can lead to toxicity.
      By: Bob Rannells
      While consuming the recommended dosage of ibuprofen is typically safe, taking more can lead to toxicity.
    • Infants younger than six months should only be given ibuprofen with a doctor's approval.
      By: dechevm
      Infants younger than six months should only be given ibuprofen with a doctor's approval.
    • Ibuprofen toxicity can lead to kidney failure.
      By: nerthuz
      Ibuprofen toxicity can lead to kidney failure.
    • Symptoms of ibuprofen toxicity may include fever.
      By: Lucky Dragon USA
      Symptoms of ibuprofen toxicity may include fever.